Dichloromethane → 2-amino-2-methyl-N-[1-(2-methyl-1-oxo-4-phenyl-2,9-diazaspiro[4.5]decan-9-yl)-1-oxo-4-phenoxybutan-2-yl]propanamide
Reaction equation
[CH3:1][C:2]([C:3](=[O:4])[NH:5][CH:6]([C:7](=[O:8])[N:9]1[CH2:10][C:11]2([CH:12]([c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[CH2:13][N:14]([CH3:17])[C:15]2=[O:16])[CH2:24][CH2:25][CH2:26]1)[CH2:27][CH2:28][O:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1)([CH3:36])[NH:37][C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44].[Cl:52][CH2:53][Cl:54].[F:45][C:46]([F:47])([F:48])[C:49]([OH:50])=[O:51]>>[CH3:1][C:2]([C:3](=[O:4])[NH:5][CH:6]([C:7](=[O:8])[N:9]1[CH2:10][C:11]2([CH:12]([c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[CH2:13][N:14]([CH3:17])[C:15]2=[O:16])[CH2:24][CH2:25][CH2:26]1)[CH2:27][CH2:28][O:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1)([CH3:36])[NH2:37]Participants
4
Sources & evidence
- ORD record
- ord-d97c27bb9603484e9453117237ffc144
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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