Methanol → 5-(4-Aminophenylamino)-2-(2,6-difluorophenyl)oxazole-4-carbonitrile

HRID 1228812Notes

Reaction equation

HRID 1228812 reaction equation
[CH3:26][OH:27].[CH3:28][CH2:29][O:30][C:31]([CH3:32])=[O:33].[F:1][c:2]1[c:3](-[c:9]2[o:10][c:11]([NH:16][c:17]3[cH:18][cH:19][c:20]([N+:23]([O-:24])=[O:25])[cH:21][cH:22]3)[c:12]([C:14]#[N:15])[n:13]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1>>[F:1][c:2]1[c:3](-[c:9]2[o:10][c:11]([NH:16][c:17]3[cH:18][cH:19][c:20]([NH2:23])[cH:21][cH:22]3)[c:12]([C:14]#[N:15])[n:13]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 887MethanolHCID 8857Ethyl AcetateHCID 595874302-(2,6-Difluorophenyl)-5-(4-nitrophenylamino)oxazole-4-carbonitrile

Product 1

HCID 595874505-(4-Aminophenylamino)-2-(2,6-difluorophenyl)oxazole-4-carbonitrile

Sources & evidence

ORD record
ord-20e571cedd2e471aae33178388936ef4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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