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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1228832Generated: October 31, 2026

Water → 5-Hydroxy-5-(2,2,2-trifluoro-ethoxymethyl)-2-(4-trifluoromethoxy-phenyl)-hexahydro-cyclopenta[c]pyrrol-1-one

https://huagongshe.com/reaction/1228832

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
Reactant2,2,2-TrifluoroethanolHCID 6409—
ReactantSodiumHCID 5360545—
Reactantrac-(3aR,5S,6aS)-2-[4-(trifluoromethoxy)phenyl]hexahydro-1H-spiro[cyclopenta[c]pyrrole-5,2'-oxiran]-1-oneHCID 86673919—
Product5-Hydroxy-5-(2,2,2-trifluoro-ethoxymethyl)-2-(4-trifluoromethoxy-phenyl)-hexahydro-cyclopenta[c]pyrrol-1-oneHCID 78078593—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-3b093375553d423880abcc43d22b7bcd
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)