Dichloromethane → Methyl 2-(2-pyrrolidinyl)methoxypyridine-5-carboxylate

HRID 122903Notes

Reaction equation

HRID 122903 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([CH2:13][O:14][c:15]2[n:16][cH:17][c:18]([C:21](=[O:22])[O:23][CH3:24])[cH:19][cH:20]2)[CH2:10][CH2:11][CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[Cl:32][CH2:33][Cl:34].[F:25][C:26]([F:27])([F:28])[C:29]([OH:30])=[O:31]>>[NH:8]1[CH:9]([CH2:13][O:14][c:15]2[n:16][cH:17][c:18]([C:21](=[O:22])[O:23][CH3:24])[cH:19][cH:20]2)[CH2:10][CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 23511704Methyl 2-[[1-(tert-butoxycarbonyl)-2-pyrrolidinyl]methoxy]pyridine-5-carboxylate

Product 1

HCID 23511785Methyl 2-(2-pyrrolidinyl)methoxypyridine-5-carboxylate

Sources & evidence

ORD record
ord-76c023eca30e4fbca9098f4e59612e98
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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