Tetrahydrofuran → (4-Methoxycarbonylphenyl) 3-(hydroxymethyl)-4-phenylpyrrolidine-1-carboxylate

HRID 1229092Notes

Reaction equation

HRID 1229092 reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH2:7][CH:8]1[CH2:9][N:10]([C:19](=[O:20])[O:21][c:22]2[cH:23][cH:24][c:25]([C:28](=[O:29])[O:30][CH3:31])[cH:26][cH:27]2)[CH2:11][CH:12]1[c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1)([CH3:5])([CH3:32])[CH3:33].[CH2:35]([N+:36]([CH2:37][CH2:38][CH2:39][CH3:40])([CH2:41][CH2:42][CH2:43][CH3:44])[CH2:45][CH2:46][CH2:47][CH3:48])[CH2:49][CH2:50][CH3:51].[CH2:52]1[O:53][CH2:54][CH2:55][CH2:56]1.[F-:34]>>[OH:6][CH2:7][CH:8]1[CH2:9][N:10]([C:19](=[O:20])[O:21][c:22]2[cH:23][cH:24][c:25]([C:28](=[O:29])[O:30][CH3:31])[cH:26][cH:27]2)[CH2:11][CH:12]1[c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 178498301HCID 178498301, compound

Product 1

HCID 174554951(4-Methoxycarbonylphenyl) 3-(hydroxymethyl)-4-phenylpyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-64338ae8e20840d894ed9bea1cd9a809
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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