Acetonitrile → 3-(3,5-Dichloro-pyridin-2-yloxy)-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one

HRID 1229229Notes

Reaction equation

HRID 1229229 reaction equation
[CH2:36]1[CH2:37][CH2:38][C:39]2=[N:44][CH2:43][CH2:42][CH2:41][N:40]2[CH2:45][CH2:46]1.[CH3:47][C:48]#[N:49].[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:8][C:9]2=[C:13]([c:14]3[cH:15][cH:16][c:17]([S:20](=[O:21])(=[O:22])[CH3:23])[cH:18][cH:19]3)[C:12]([CH3:24])([CH3:25])[O:11][C:10]2=[O:26])[n:6][cH:7]1.[Cl:27][c:28]1[c:29](=[O:30])[nH:31][cH:32][c:33]([Cl:34])[cH:35]1>>[Cl:1][c:2]1[cH:3][c:4]([Cl:27])[c:5]([O:8][C:9]2=[C:13]([c:14]3[cH:15][cH:16][c:17]([S:20](=[O:21])(=[O:22])[CH3:23])[cH:18][cH:19]3)[C:12]([CH3:24])([CH3:25])[O:11][C:10]2=[O:26])[n:6][cH:7]1

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 794963,5-Dichloro-2-pyridoneHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 101574273-(5-Chloro-2-pyridyloxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)-5H-furan-2-one

Product 1

HCID 219485213-(3,5-Dichloro-pyridin-2-yloxy)-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one

Sources & evidence

ORD record
ord-fbf70712b4f24a5798f4bcf8692f6824
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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