Hydrochloric Acid → N-[(2-methoxynaphthalen-1-yl)methyl]-N-methyl-3-(7-oxo-6,8-dihydro-5H-1,8-naphthyridin-3-yl)prop-2-enamide

HRID 1229259Notes

Reaction equation

HRID 1229259 reaction equation
[CH3:16][NH:17][CH2:18][c:19]1[cH:20][cH:21][c:22]2[c:23]([cH:24][cH:25][cH:26][cH:27]2)[c:28]1[CH2:29][CH2:30][CH3:31].[CH3:1][O:2][c:3]1[c:4]([CH2:13][NH:14][CH3:15])[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[cH:11][cH:12]1.[CH3:50][N:51]1[CH2:52][c:53]2[cH:54][c:55]([CH:56]=[CH:57][C:58]([OH:59])=[O:60])[cH:61][n:62][c:63]2[NH:64][C:65](=[O:66])[CH2:67]1.[ClH:32].[ClH:49].[O:33]=[C:34]1[CH2:35][CH2:36][c:37]2[cH:38][c:39]([CH:44]=[CH:45][C:46](=[O:47])[OH:48])[cH:40][n:41][c:42]2[NH:43]1>>[CH3:1][O:2][c:3]1[c:4]([CH2:13][N:14]([CH3:15])[C:46]([CH:45]=[CH:44][c:39]2[cH:38][c:37]3[c:42]([n:41][cH:40]2)[NH:43][C:34](=[O:33])[CH2:35][CH2:36]3)=[O:48])[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[cH:11][cH:12]1

Participants

6

Reactant 5

HCID 313Hydrochloric Acid2×HCID 5983882-Methoxy-N-methyl-1-naphthalenemethanamineHCID 59456959Methyl-(1-propyl-naphthalen-2-ylmethyl)amineHCID 66905303(E)-3-(7-oxo-1,5,6,7-tetrahydro-1,8-naphthyridin-3-yl)acrylic acidHCID 669662013-(4-Methyl-2-oxo-2,3,4,5-tetrahydro-1H-pyrido[2,3-e][1,4]diazepin-7-yl)-acrylic acid

Product 1

HCID 66967552N-[(2-methoxynaphthalen-1-yl)methyl]-N-methyl-3-(7-oxo-6,8-dihydro-5H-1,8-naphthyridin-3-yl)prop-2-enamide

Sources & evidence

ORD record
ord-6bb3f01a23ee49deb2cba576ae73c3a6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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