Methanol → 1-Benzyl 4-tert-butyl 2-methyl piperazine-1,2,4-tricarboxylate

HRID 1229503Notes

Reaction equation

HRID 1229503 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([C:24](=[O:25])[OH:26])[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]1.[CH3:27][Si:28]([CH:29]=[N+:30]=[N-:31])([CH3:32])[CH3:33].[CH3:34][OH:35]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([C:24](=[O:25])[O:26][CH3:27])[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]1

Participants

4

Reactant 3

HCID 887MethanolHCID 167693TrimethylsilyldiazomethaneHCID 2756777N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid

Product 1

HCID 44519651-Benzyl 4-tert-butyl 2-methyl piperazine-1,2,4-tricarboxylate

Sources & evidence

ORD record
ord-fb8efc55b18e457da738230348960ec7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…