Tetrahydrofuran → tert-Butyl 3-hydroxy-3-methylazetidine-1-carboxylate

HRID 1229569Notes

Reaction equation

HRID 1229569 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][C:10](=[O:12])[CH2:11]1.[CH2:16]1[O:17][CH2:18][CH2:19][CH2:20]1.[CH3:13][Mg:14][Cl:15]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][C:10]([OH:12])([CH3:13])[CH2:11]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 15194043-Oxo-azetidine-1-carboxylic acid tert-butyl esterHCID 178418332HCID 178418332, compound

Product 1

HCID 54751705tert-Butyl 3-hydroxy-3-methylazetidine-1-carboxylate

Sources & evidence

ORD record
ord-91b2c1b3027242da83fef0469191b264
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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