2-Amino-2-methyl-1-propanol → 6-Cyclopropylmethoxy-5-(tetrahydro-furan-3-yl)-pyridine-2-carboxylic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide

HRID 1229602Notes

Reaction equation

HRID 1229602 reaction equation
[C:39]([CH:40]([NH:41][C:42]([c:43]1[cH:44][cH:45][c:46]([CH:47]2[CH2:48][CH2:49][O:50][CH2:51]2)[c:52]([O:53][CH2:54][CH:55]2[CH2:56][CH2:57]2)[n:58]1)=[O:59])[CH2:60][CH:61]([CH3:62])[CH3:63])(=[O:64])[NH2:65].[CH:1]1([CH2:4][O:5][c:6]2[c:7]([CH:15]3[CH2:16][O:17][CH2:18][CH2:19]3)[cH:8][cH:9][c:10]([C:12](=[O:13])[OH:14])[n:11]2)[CH2:2][CH2:3]1.[CH:20]1([CH2:21][O:22][c:23]2[n:24][c:25]([C:26]([OH:27])=[O:28])[cH:29][cH:30][c:31]2[CH:32]2[CH2:33][CH2:34][CH2:35][O:36]2)[CH2:37][CH2:38]1.[NH2:66][C:67]([CH2:68][OH:69])([CH3:70])[CH3:71]>>[CH:1]1([CH2:4][O:5][c:6]2[c:7]([CH:15]3[CH2:16][O:17][CH2:18][CH2:19]3)[cH:8][cH:9][c:10]([C:12](=[O:14])[NH:66][C:67]([CH2:68][OH:69])([CH3:70])[CH3:71])[n:11]2)[CH2:2][CH2:3]1

Participants

5

Reactant 4

HCID 118072-Amino-2-methyl-1-propanolHCID 710873686-(Cyclopropylmethoxy)-5-(tetrahydrofuran-2-yl)-pyridine-2-carboxylic acidHCID 710873756-(Cyclopropylmethoxy)-5-(tetrahydrofuran-3-yl)-pyridine-2-carboxylic acidHCID 78010113N-(1-amino-4-methyl-1-oxopentan-2-yl)-6-(cyclopropylmethoxy)-5-(oxolan-3-yl)pyridine-2-carboxamide

Product 1

HCID 711056216-Cyclopropylmethoxy-5-(tetrahydro-furan-3-yl)-pyridine-2-carboxylic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide

Sources & evidence

ORD record
ord-8db81855bbff4d8c9fe90192aa972168
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…