Dichloromethane → 4-[6-(5-Methanesulfonyl-2,3-dihydro-indol-1-yl)-pyrimidin-4-ylamino]-piperidine-1-carboxylic acid isopropyl ester
Reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][c:7]2[c:11]([cH:12][cH:13]1)[N:10]([c:14]1[cH:15][c:16]([NH:20][CH:21]3[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]3)[n:17][cH:18][n:19]1)[CH2:9][CH2:8]2.[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[Cl:34][C:35](=[O:36])[O:37][CH:38]([CH3:39])[CH3:40].[Cl:41][CH2:42][Cl:43]>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][c:7]2[c:11]([cH:12][cH:13]1)[N:10]([c:14]1[cH:15][c:16]([NH:20][CH:21]3[CH2:22][CH2:23][N:24]([C:35](=[O:36])[O:37][CH:38]([CH3:39])[CH3:40])[CH2:25][CH2:26]3)[n:17][cH:18][n:19]1)[CH2:9][CH2:8]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-f55907e2f41f4548bb57eca50b4c3376
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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