Potassium Cation → Tert-butyl 3-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazol-1-yl]pyrrolidine-1-carboxylate

HRID 1229707Notes

Reaction equation

HRID 1229707 reaction equation
[Br:1][CH:2]1[CH2:3][N:4]([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:5][CH2:6]1.[C:14](=[O:15])([O-:16])[O-:17].[K+:18].[K+:19].[NH2:56][NH2:57].[O:58]=[CH:59][N:60]([CH3:61])[CH3:62].[OH2:55].[o:20]1[c:21](-[c:25]2[cH:26][c:27]([C:30]([F:31])([F:32])[F:33])[n:28][nH:29]2)[cH:22][cH:23][cH:24]1.[o:34]1[cH:35][cH:36][cH:37][c:38]1-[c:39]1[n:40](-[c:41]2[cH:42][c:43]([C:44]#[N:45])[s:46][cH:47]2)[n:48][c:49]([C:50]([F:51])([F:52])[F:53])[cH:54]1>>[CH:2]1([n:29]2[c:25](-[c:21]3[o:20][cH:24][cH:23][cH:22]3)[cH:26][c:27]([C:30]([F:31])([F:32])[F:33])[n:28]2)[CH2:3][N:4]([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:5][CH2:6]1

Participants

9

Reactant 8

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 9321HydrazineHCID 19660Carbonate IonHCID 426142173-Bromo-pyrrolidine-1-carboxylic acid tert-butyl esterHCID 598432044-(5-(furan-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)thiophene-2-carbonitrileHCID 178506075HCID 178506075, compound

Product 1

HCID 69300890Tert-butyl 3-[5-(furan-2-yl)-3-(trifluoromethyl)pyrazol-1-yl]pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-f91ae280d5f54cd3a2e40bbc0bad7c92
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…