Hydroxide → 6-tert-Butyl-2-{3-[5-(5-ethanesulfonyl-pyridin-2-ylamino)-1-methyl-6-oxo-1,6-dihydro-pyridazin-3-yl]-2-hydroxymethyl-phenyl}-8-fluoro-2H-phthalazin-1-one
Reaction equation
[C:1](=[O:2])([CH3:3])[O:4][CH2:5][c:6]1[c:7](-[n:32]2[c:33](=[O:47])[c:34]3[c:35]([F:46])[cH:36][c:37]([C:42]([CH3:43])([CH3:44])[CH3:45])[cH:38][c:39]3[cH:40][n:41]2)[cH:8][cH:9][cH:10][c:11]1-[c:12]1[n:13][n:14]([CH3:31])[c:15](=[O:30])[c:16]([NH:18][c:19]2[n:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[CH2:28][CH3:29])[cH:23][cH:24]2)[cH:17]1.[Li+:49].[O:50]1[CH2:51][CH2:52][O:53][CH2:54][CH2:55]1.[OH-:48]>>[OH:4][CH2:5][c:6]1[c:7](-[n:32]2[c:33](=[O:47])[c:34]3[c:35]([F:46])[cH:36][c:37]([C:42]([CH3:43])([CH3:44])[CH3:45])[cH:38][c:39]3[cH:40][n:41]2)[cH:8][cH:9][cH:10][c:11]1-[c:12]1[n:13][n:14]([CH3:31])[c:15](=[O:30])[c:16]([NH:18][c:19]2[n:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[CH2:28][CH3:29])[cH:23][cH:24]2)[cH:17]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-50db29d6c8b84a51aa9f77a96bbddafb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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