Methylamine → 1-(4-Chloro-phenyl)-2-methylamino-1-[4-(1H-pyrazol-4-yl)-phenyl]-ethanol

HRID 1230321Notes

Reaction equation

HRID 1230321 reaction equation
[CH3:46][NH2:47].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6]([c:7]2[cH:8][cH:9][c:10]([I:11])[cH:12][cH:13]2)([OH:14])[CH2:15][NH:16][CH2:17][CH2:18][OH:19])[cH:20][cH:21]1.[Cl:22][c:23]1[cH:24][cH:25][c:26]([C:29]2([c:35]3[cH:36][cH:37][c:38](-[c:41]4[cH:42][n:43][nH:44][cH:45]4)[cH:39][cH:40]3)[O:30][CH2:31][CH2:32][NH:33][CH2:34]2)[cH:27][cH:28]1>>[Cl:22][c:23]1[cH:24][cH:25][c:26]([C:29]([OH:30])([CH2:34][NH:33][CH3:32])[c:35]2[cH:36][cH:37][c:38](-[c:41]3[cH:42][nH:43][n:44][cH:45]3)[cH:39][cH:40]2)[cH:27][cH:28]1

Participants

4

Reactant 3

HCID 6329MethylamineHCID 114619212-(4-Chloro-phenyl)-2-[4-(1H-pyrazol-4-yl)-phenyl]-morpholineHCID 593319671-(4-Chloro-phenyl)-2-(2-hydroxy-ethylamino)-1-(4-iodo-phenyl)-ethanol

Product 1

HCID 113818461-(4-Chloro-phenyl)-2-methylamino-1-[4-(1H-pyrazol-4-yl)-phenyl]-ethanol

Sources & evidence

ORD record
ord-d08e39bdc5d54be9b2d93251a3a3ee1d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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