Dichloromethane → N-[3-(3-Acetylthio-2-methylpropanoyl thio)-2-methyl-propanoyl]-N-cyclopentyl glycine-t-butyl ester

HRID 1230689Notes

Reaction equation

HRID 1230689 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][N:8]([CH:9]1[CH2:10][CH2:11][CH2:12][CH2:13]1)[C:14]([CH:15]([CH2:16][SH:17])[CH3:18])=[O:19])=[O:20].[C:28]([CH3:29])(=[O:30])[S:31][CH2:32][CH:33]([C:34](=[O:35])[Cl:36])[CH3:37].[CH2:38]([Cl:39])[Cl:40].[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][N:8]([CH:9]1[CH2:10][CH2:11][CH2:12][CH2:13]1)[C:14]([CH:15]([CH2:16][S:17][C:34]([CH:33]([CH2:32][S:31][C:28]([CH3:29])=[O:30])[CH3:37])=[O:35])[CH3:18])=[O:19])=[O:20]

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 103458Ethanethioic acid, S-(3-chloro-2-methyl-3-oxopropyl) esterHCID 13469597N-(3-mercapto-2-methylpropanoyl)-N-cyclopentylglycine t-butyl ester

Product 1

HCID 20037734N-[3-(3-Acetylthio-2-methylpropanoyl thio)-2-methyl-propanoyl]-N-cyclopentyl glycine-t-butyl ester

Sources & evidence

ORD record
ord-7d0a6a90cce3427fa0c748145da6dba8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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