Acetic Acid → Ethyl 1-cyclopropyl-7-[2-[5-(2,4-diamino-pyrimidin-5-yl-methyl)-2,3-dimethoxy-phenyl]ethyl]-6,8-difluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylate
Reaction equation
[CH3:45][N:46]([CH3:47])[CH:48]=[O:49].[CH3:50][C:51](=[O:52])[OH:53].[CH:1]1([n:4]2[cH:5][c:6]([C:38](=[O:39])[O:40][CH2:41][CH3:42])[c:7](=[O:37])[c:8]3[cH:9][c:10]([F:36])[c:11]([C:15]#[C:16][c:17]4[c:18]([O:34][CH3:35])[c:19]([O:32][CH3:33])[cH:20][c:21]([CH2:23][c:24]5[c:25]([NH2:31])[n:26][c:27]([NH2:30])[n:28][cH:29]5)[cH:22]4)[c:12]([F:14])[c:13]23)[CH2:2][CH2:3]1.[H:43][H:44]>>[CH:1]1([n:4]2[cH:5][c:6]([C:38](=[O:39])[O:40][CH2:41][CH3:42])[c:7](=[O:37])[c:8]3[cH:9][c:10]([F:36])[c:11]([CH2:15][CH2:16][c:17]4[c:18]([O:34][CH3:35])[c:19]([O:32][CH3:33])[cH:20][c:21]([CH2:23][c:24]5[c:25]([NH2:31])[n:26][c:27]([NH2:30])[n:28][cH:29]5)[cH:22]4)[c:12]([F:14])[c:13]23)[CH2:2][CH2:3]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-50dade5a22ab4ca98f6ca8781c0b03f5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…