Chloroform → 7-(5-Acetamidomethyl-2-isoindolinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester
Reaction equation
[C:22]([CH3:23])(=[O:24])[NH:25][CH2:26][c:27]1[cH:28][c:29]2[c:33]([cH:34][cH:35]1)[CH2:32][NH:31][CH2:30]2.[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][n:8]([CH:19]2[CH2:20][CH2:21]2)[c:9]2[n:10][c:11]([Cl:18])[c:12]([F:17])[cH:13][c:14]2[c:15]1=[O:16].[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[CH:43]([Cl:44])([Cl:45])[Cl:46]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][n:8]([CH:19]2[CH2:20][CH2:21]2)[c:9]2[n:10][c:11]([N:31]3[CH2:30][c:29]4[cH:28][c:27]([CH2:26][NH:25][C:22]([CH3:23])=[O:24])[cH:35][cH:34][c:33]4[CH2:32]3)[c:12]([F:17])[cH:13][c:14]2[c:15]1=[O:16]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-c8c84038868f45e9979ef4fc8b3d7a06
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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