Tetrahydrofuran → 6-{(SR)-1-[(3RS,4SR)-1-Benzyl-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-ethoxy}-nicotinonitrile

HRID 1231090노트

반응식

[CH2:29]([c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1)[N:36]1[CH2:37][CH:38]([CH:49]([CH3:50])[OH:51])[CH:39]([c:41]2[cH:42][c:43]([Cl:48])[c:44]([Cl:47])[cH:45][cH:46]2)[CH2:40]1.[CH2:52]1[O:53][CH2:54][CH2:55][CH2:56]1.[OH:20][c:21]1[n:22][cH:23][c:24]([C:25]#[N:26])[cH:27][cH:28]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[O:20]([c:21]1[n:22][cH:23][c:24]([C:25]#[N:26])[cH:27][cH:28]1)[CH:49]([CH:38]1[CH2:37][N:36]([CH2:29][c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[CH2:40][CH:39]1[c:41]1[cH:42][c:43]([Cl:48])[c:44]([Cl:47])[cH:45][cH:46]1)[CH3:50]