Ethanol → 3-[4-(2-Hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one
Reaction equation
[CH2:39]1[O:40][CH2:41][CH2:42][O:43][CH2:44]1.[CH3:28][O:29][c:30]1[n:31][cH:32][c:33]([B:36]([OH:37])[OH:38])[cH:34][cH:35]1.[CH3:45][CH2:46][OH:47].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([N:17]3[CH2:18][CH2:19][N:20]([CH2:23][CH2:24][OH:25])[CH2:21][CH2:22]3)[c:8](=[O:16])[n:9]2[CH2:10][CH2:11][O:12][CH2:13][CH2:14][CH3:15])[cH:26][n:27]1.[Na+:48].[Na+:49].[O-:50][C:51](=[O:52])[O-:53].[Pd:54].[c:112]1([P:113]([c:114]2[cH:115][cH:116][cH:117][cH:118][cH:119]2)[c:120]2[cH:121][cH:122][cH:123][cH:124][cH:125]2)[cH:126][cH:127][cH:128][cH:129][cH:130]1.[c:55]1([P:56]([c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[cH:69][cH:70][cH:71][cH:72][cH:73]1.[c:74]1([P:75]([c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)[c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)[cH:88][cH:89][cH:90][cH:91][cH:92]1.[c:93]1([P:94]([c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)[c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)[cH:107][cH:108][cH:109][cH:110][cH:111]1>>[c:2]1(-[c:33]2[cH:32][n:31][c:30]([O:29][CH3:28])[cH:35][cH:34]2)[cH:3][c:4]2[c:5]([n:6][c:7]([N:17]3[CH2:18][CH2:19][N:20]([CH2:23][CH2:24][OH:25])[CH2:21][CH2:22]3)[c:8](=[O:16])[n:9]2[CH2:10][CH2:11][O:12][CH2:13][CH2:14][CH3:15])[cH:26][n:27]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-e7ace84ddec642e9898cdb9524188d1e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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