Acetonitrile → tert-butyl N-[2-hydroxy-2-(4-hydroxy-2-oxo-3H-1,3-benzothiazol-7-yl)ethyl]-N-[[4-[2-[4-(2-propan-2-yl-1,3-thiazole-5-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl]ethoxy]phenyl]methyl]carbamate

反応式

[CH3:1][S:2]([O:3][CH2:6][CH2:7][O:8][c:9]1[cH:10][cH:11][c:12]([CH2:15][N:16]([CH2:17][CH:18]([c:19]2[cH:20][cH:21][c:22]([OH:29])[c:23]3[nH:24][c:25](=[O:28])[s:26][c:27]23)[OH:30])[C:31](=[O:32])[O:33][C:34]([CH3:35])([CH3:36])[CH3:37])[cH:13][cH:14]1)(=[O:4])=[O:5].[CH3:59][CH2:60][N:61]([CH2:62][CH3:63])[CH2:64][CH3:65].[CH3:66][C:67]#[N:68].[CH:38]([CH3:39])([CH3:40])[c:41]1[s:42][c:43]([C:46](=[O:47])[N:48]2[CH2:49][CH2:50][O:51][C:52]3([CH2:53]2)[CH2:54][CH2:55][NH:56][CH2:57][CH2:58]3)[cH:44][n:45]1>>[CH2:6]([CH2:7][O:8][c:9]1[cH:10][cH:11][c:12]([CH2:15][N:16]([CH2:17][CH:18]([c:19]2[cH:20][cH:21][c:22]([OH:29])[c:23]3[nH:24][c:25](=[O:28])[s:26][c:27]23)[OH:30])[C:31](=[O:32])[O:33][C:34]([CH3:35])([CH3:36])[CH3:37])[cH:13][cH:14]1)[N:56]1[CH2:55][CH2:54][C:52]2([O:51][CH2:50][CH2:49][N:48]([C:46]([c:43]3[s:42][c:41]([CH:38]([CH3:39])[CH3:40])[n:45][cH:44]3)=[O:47])[CH2:53]2)[CH2:58][CH2:57]1