Trifluoroacetic acid → 4-(4-Fluorophenyl)-1-[2-(piperidin-4-yl)-ethenylsulphonyl]-piperazine

HRID 1231199Notes

Reaction equation

HRID 1231199 reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([S:14](=[O:15])(=[O:16])[CH:17]=[CH:18][CH:19]3[CH2:20][CH2:21][N:22]([C:25]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[CH2:23][CH2:24]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1.[OH:32][C:33]([C:34]([F:35])([F:36])[F:37])=[O:38]>>[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([S:14](=[O:15])(=[O:16])[CH:17]=[CH:18][CH:19]3[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 541807894-(4-Fluorophenyl)-1-[2-(1-t-butoxycarbonylpiperidin-4-yl)-ethenylsulphonyl]-piperazine

Product 1

HCID 541755954-(4-Fluorophenyl)-1-[2-(piperidin-4-yl)-ethenylsulphonyl]-piperazine

Sources & evidence

ORD record
ord-67a82c35a31e4672923bc8ec19b8768d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…