Hydrochloric Acid → Tert-butyl 4-[2-methyl-5-[2-(2-pyrrolidin-1-ylethoxy)phenyl]phenyl]piperazine-1-carboxylate

HRID 1231487Notes

Reaction equation

HRID 1231487 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][c:16](-[c:21]3[c:22]([OH:27])[cH:23][cH:24][cH:25][cH:26]3)[cH:17][cH:18][c:19]2[CH3:20])[CH2:12][CH2:13]1.[Cl:35][CH2:36][CH2:37][N:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1.[ClH:34].[K+:28].[K+:29].[O-:30][C:31]([O-:32])=[O:33]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][c:16](-[c:21]3[c:22]([O:27][CH2:36][CH2:37][N:38]4[CH2:39][CH2:40][CH2:41][CH2:42]4)[cH:23][cH:24][cH:25][cH:26]3)[cH:17][cH:18][c:19]2[CH3:20])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 816691-(2-Chloroethyl)pyrrolidineHCID 69243961Tert-butyl 4-[5-(2-hydroxyphenyl)-2-methylphenyl]piperazine-1-carboxylate

Product 1

HCID 69242357Tert-butyl 4-[2-methyl-5-[2-(2-pyrrolidin-1-ylethoxy)phenyl]phenyl]piperazine-1-carboxylate

Sources & evidence

ORD record
ord-ecb9a8472caf4a5eb8e161f936226744
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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