Methanol → 3-(6-Bromo-2-fluoro-3-hydroxymethyl-phenoxy)-5-chloro-benzonitrile
Reaction equation
[BH4-:1].[Br:3][c:4]1[cH:5][cH:6][c:7]([CH:21]=[O:22])[c:8]([F:20])[c:9]1[O:10][c:11]1[cH:12][c:13]([C:14]#[N:15])[cH:16][c:17]([Cl:19])[cH:18]1.[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH3:28][OH:29].[Na+:2]>>[Br:3][c:4]1[cH:5][cH:6][c:7]([CH2:21][OH:22])[c:8]([F:20])[c:9]1[O:10][c:11]1[cH:12][c:13]([C:14]#[N:15])[cH:16][c:17]([Cl:19])[cH:18]1Participants
6
Sources & evidence
- ORD record
- ord-25d4671fdf4d487580cd1f01d073e480
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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