Ethyl Acetate → 3-[[2-Amino-5-(trifluoromethoxy)phenyl]methyl]-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one

HRID 1231638Notes

Reaction equation

HRID 1231638 reaction equation
[CH3:37][CH2:38][O:39][C:40]([CH3:41])=[O:42].[F:1][C:2]([c:3]1[cH:4][c:5]([CH:13]2[CH:14]([CH3:34])[N:15]([CH2:19][c:20]3[c:21]([N+:31]([O-:32])=[O:33])[cH:22][cH:23][c:24]([O:26][C:27]([F:28])([F:29])[F:30])[cH:25]3)[C:16](=[O:18])[O:17]2)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:35])[F:36]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH:13]2[CH:14]([CH3:34])[N:15]([CH2:19][c:20]3[c:21]([NH2:31])[cH:22][cH:23][c:24]([O:26][C:27]([F:28])([F:29])[F:30])[cH:25]3)[C:16](=[O:18])[O:17]2)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:35])[F:36]

Participants

3

Reactant 2

HCID 8857Ethyl AcetateHCID 877921465-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-3-[[2-nitro-5-(trifluoromethoxy)phenyl]methyl]-1,3-oxazolidin-2-one

Product 1

HCID 766267923-[[2-Amino-5-(trifluoromethoxy)phenyl]methyl]-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-02d147f6d8ae46ac9e0a0188b1be7e05
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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