2-Pyrazinecarboxylic acid → [5-(2-{[N-ethyl-N-(pyrazine-2-carbonyl)-amino]-methyl}-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester

HRID 1231765Notes

Reaction equation

HRID 1231765 reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[cH:7][n:8][cH:9][c:10](-[c:12]2[c:13]([CH2:22][NH:23][CH2:24][CH3:25])[cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[cH:11]1)=[O:26].[n:27]1[c:28]([C:33](=[O:34])[OH:35])[cH:29][n:30][cH:31][cH:32]1>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[cH:7][n:8][cH:9][c:10](-[c:12]2[c:13]([CH2:22][N:23]([CH2:24][CH3:25])[C:33]([c:28]3[n:27][cH:32][cH:31][n:30][cH:29]3)=[O:35])[cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[cH:11]1)=[O:26]

Participants

3

Reactant 2

HCID 10472-Pyrazinecarboxylic acidHCID 67212445[5-(2-Ethylaminomethyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester

Product 1

HCID 67212438[5-(2-{[N-ethyl-N-(pyrazine-2-carbonyl)-amino]-methyl}-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester

Sources & evidence

ORD record
ord-159711706b7847728401501ba0272f0b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…