Borane → tert-Butyl 4-(hydroxymethyl)phenethylcarbamate

HRID 1231875Notes

Reaction equation

HRID 1231875 reaction equation
[BH3:6].[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17](=[O:18])[NH:19][CH2:20][CH2:21][c:22]1[cH:23][cH:24][c:25]([C:26](=[O:27])[OH:28])[cH:29][cH:30]1.[O:1]1[CH2:2][CH2:3][CH2:4][CH2:5]1.[O:7]1[CH2:8][CH2:9][CH2:10][CH2:11]1>>[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17](=[O:18])[NH:19][CH2:20][CH2:21][c:22]1[cH:23][cH:24][c:25]([CH2:26][OH:27])[cH:29][cH:30]1

Participants

4

Reactant 3

HCID 6331BoraneHCID 8028Tetrahydrofuran2×HCID 166409054-(2-{[(Tert-butoxy)carbonyl]amino}ethyl)benzoic acid

Product 1

HCID 22337080tert-Butyl 4-(hydroxymethyl)phenethylcarbamate

Sources & evidence

ORD record
ord-3429f06d5ba647bea895ae81b6020003
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…