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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1231972Generated: October 31, 2026

2-chloro-N4-(3-chloro-4-trifluoromethoxyphenyl)-5-fluoro-4-pyrimidineamine → N4-(3-chloro-4-trifluoromethoxyphenyl)-5-fluoro-N2-[2,3-dihydro-2-(methoxycarbonyl)benzofuran-5-yl]-2,4-primidinediamine

https://huagongshe.com/reaction/1231972

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-chloro-N4-(3-chloro-4-trifluoromethoxyphenyl)-5-fluoro-4-pyrimidineamineHCID 22060462—
ReactantMethyl 5-amino-2,3-dihydrobenzofuran-2-carboxylateHCID 22060823—
ProductN4-(3-chloro-4-trifluoromethoxyphenyl)-5-fluoro-N2-[2,3-dihydro-2-(methoxycarbonyl)benzofuran-5-yl]-2,4-primidinediamineHCID 10174439—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-5a0f2d4f4ed94d33b252ffaf636af661
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)