1-Octyne → Ethyl 3-(5-(oct-1-ynyl)indoline-1-carboxamido)propanoate

HRID 1232116Notes

Reaction equation

HRID 1232116 reaction equation
[CH:21]#[C:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28].[Cu:29][I:30].[I:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([C:11](=[O:12])[NH:13][CH2:14][CH2:15][C:16](=[O:17])[O:18][CH2:19][CH3:20])[CH2:6][CH2:5]2>>[c:2]1([C:21]#[C:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([C:11](=[O:12])[NH:13][CH2:14][CH2:15][C:16](=[O:17])[O:18][CH2:19][CH3:20])[CH2:6][CH2:5]2

Participants

4

Reactant 3

HCID 123701-OctyneHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66614968Ethyl 3-(5-iodoindoline-1-carboxamido)propanoate

Product 1

HCID 66615094Ethyl 3-(5-(oct-1-ynyl)indoline-1-carboxamido)propanoate

Sources & evidence

ORD record
ord-a92edee0290e4f68b17b4e262f8b4649
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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