Water → N-(3-fluoro-4-(7-(3-(1-hydroxycyclopropyl)propoxy)quinolin-4-yloxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide
Reaction equation
[C:49](=[O:50])([O-:51])[O-:52].[CH3:1][S:2](=[O:3])(=[O:4])[O:5][CH2:6][CH2:7][CH2:8][C:9]1([OH:12])[CH2:10][CH2:11]1.[CH3:55][N:56]([CH3:57])[C:58](=[O:59])[CH3:60].[Cs+:53].[Cs+:54].[F:13][c:14]1[cH:15][c:16]([NH:32][C:33](=[O:34])[c:35]2[c:36](=[O:48])[n:37](-[c:42]3[cH:43][cH:44][cH:45][cH:46][cH:47]3)[n:38]([CH3:41])[c:39]2[CH3:40])[cH:17][cH:18][c:19]1[O:20][c:21]1[cH:22][cH:23][n:24][c:25]2[cH:26][c:27]([OH:31])[cH:28][cH:29][c:30]12.[OH2:61]>>[O:5]([CH2:6][CH2:7][CH2:8][C:9]1([OH:12])[CH2:10][CH2:11]1)[c:27]1[cH:26][c:25]2[n:24][cH:23][cH:22][c:21]([O:20][c:19]3[c:14]([F:13])[cH:15][c:16]([NH:32][C:33](=[O:34])[c:35]4[c:36](=[O:48])[n:37](-[c:42]5[cH:43][cH:44][cH:45][cH:46][cH:47]5)[n:38]([CH3:41])[c:39]4[CH3:40])[cH:17][cH:18]3)[c:30]2[cH:29][cH:28]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b2d37b1236294614bc3af5a91b7a2753
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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