2,4-Dichlorobenzylamine → Methyl 2-(2,4-dichlorobenzylamino)-4-(trifluoromethyl)pyrimidine-5-carboxylate

HRID 1232241Notes

Reaction equation

HRID 1232241 reaction equation
[CH2:26]1[O:27][CH2:28][CH2:29][O:30][CH2:31]1.[CH3:32][CH2:33][O:34][C:35](=[O:36])[CH3:37].[Cl:16][c:17]1[c:18]([CH2:19][NH2:20])[cH:21][cH:22][c:23]([Cl:25])[cH:24]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([C:12](=[O:13])[O:14][CH3:15])[c:6]([C:8]([F:9])([F:10])[F:11])[n:7]1>>[c:2]1([NH:20][CH2:19][c:18]2[c:17]([Cl:16])[cH:24][c:23]([Cl:25])[cH:22][cH:21]2)[n:3][cH:4][c:5]([C:12](=[O:13])[O:14][CH3:15])[c:6]([C:8]([F:9])([F:10])[F:11])[n:7]1

Participants

5

Reactant 4

HCID 14852,4-DichlorobenzylamineHCID 8857Ethyl AcetateHCID 312751,4-DioxaneHCID 3696469Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate

Product 1

HCID 58168975Methyl 2-(2,4-dichlorobenzylamino)-4-(trifluoromethyl)pyrimidine-5-carboxylate

Sources & evidence

ORD record
ord-0d2e27957b3f4739bb89a53498f8da55
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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