Chloride → 1-(2-Bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-2,2-dimethylpropan-1-one
Reaction equation
[Br:1][c:2]1[n:3][c:4]2[cH:5][cH:6][nH:7][c:8]2[n:9][cH:10]1.[C:17]([C:18]([CH3:19])([CH3:20])[CH3:21])(=[O:22])[Cl:23].[CH2:12]([Al+:13][CH2:14][CH3:15])[CH3:16].[Cl-:11].[Cl:29][CH2:30][Cl:31].[Na+:28].[O-:24][C:25]([OH:26])=[O:27]>>[Br:1][c:2]1[n:3][c:4]2[c:5]([C:17]([C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[cH:6][nH:7][c:8]2[n:9][cH:10]1Participants
8
Sources & evidence
- ORD record
- ord-bd072b1a683e42158d93fea2f588137a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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