Water → N-acetyl-2-chloro-3-(1-cyanocyclopropyl)-N-[5-({2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}oxy)-2-fluorophenyl]benzamide
Reaction equation
[CH3:39][C:40](=[O:41])[O:42][C:43](=[O:44])[CH3:45].[CH3:53][N:54]([CH3:55])[c:56]1[cH:57][cH:58][n:59][cH:60][cH:61]1.[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[c:8]([F:29])[cH:9][cH:10][c:11]([O:13][c:14]3[cH:15][cH:16][c:17]4[c:18]([n:19]3)[s:20][c:21]([NH:23][C:24](=[O:25])[CH:26]3[CH2:27][CH2:28]3)[n:22]4)[cH:12]2)[cH:30][cH:31][cH:32][c:33]1[C:34]1([C:37]#[N:38])[CH2:35][CH2:36]1.[OH2:46].[cH:47]1[cH:48][cH:49][n:50][cH:51][cH:52]1>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[N:6]([c:7]2[c:8]([F:29])[cH:9][cH:10][c:11]([O:13][c:14]3[cH:15][cH:16][c:17]4[c:18]([n:19]3)[s:20][c:21]([NH:23][C:24](=[O:25])[CH:26]3[CH2:27][CH2:28]3)[n:22]4)[cH:12]2)[C:40]([CH3:39])=[O:41])[cH:30][cH:31][cH:32][c:33]1[C:34]1([C:37]#[N:38])[CH2:35][CH2:36]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-bb17fe4b49f14a3a874bf9be7e94c6f6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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