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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1232811Generated: October 30, 2026

Dimethylformamide → 4-chloro-8-(2,4-difluorophenyl)-2-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one

https://huagongshe.com/reaction/1232811

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantSerinolHCID 68294—
Reactant4-chloro-8-(2,4-difluorophenyl)-2-(methylsulfinyl)pyrido[2,3-d]pyrimidin-7(8H)-oneHCID 11951349—
Product4-chloro-8-(2,4-difluorophenyl)-2-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-oneHCID 11951516—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-54b5474896e648a6be53d8f37fcbc9ae
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)