Bromide ion → 3-{3-[(4-Tert-butyl-phenyl)-hydroxy-methyl]-pyridin-4-yl)-benzonitrile

HRID 1233032Notes

Reaction equation

HRID 1233032 reaction equation
[Br-:17].[C:18]([CH3:19])([CH3:20])([CH3:21])[c:22]1[cH:23][cH:24][c:25]([Mg+:28])[cH:26][cH:27]1.[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH:1](=[O:2])[c:3]1[cH:4][n:5][cH:6][cH:7][c:8]1-[c:9]1[cH:10][c:11]([C:12]#[N:13])[cH:14][cH:15][cH:16]1>>[CH:1]([OH:2])([c:3]1[cH:4][n:5][cH:6][cH:7][c:8]1-[c:9]1[cH:10][c:11]([C:12]#[N:13])[cH:14][cH:15][cH:16]1)[c:25]1[cH:24][cH:23][c:22]([C:18]([CH3:19])([CH3:20])[CH3:21])[cH:27][cH:26]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 592052083-(3-Formyl-pyridin-4-yl)-benzonitrileHCID 178440988HCID 178440988, compound

Product 1

HCID 592052063-{3-[(4-Tert-butyl-phenyl)-hydroxy-methyl]-pyridin-4-yl)-benzonitrile

Sources & evidence

ORD record
ord-e1ea01d08dd8400297cdedd9c42a2b43
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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