Sodium ion → 2-Methoxy-4-[2-(4-trifluoromethyl-phenyl)-4-(4-trifluoromethyl-piperidin-1-ylmethyl)-thiazol-5-ylmethoxy]-benzonitrile
Reaction equation
[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[s:10][c:11]([CH2:25][OH:26])[c:12]([CH2:14][N:15]3[CH2:16][CH2:17][CH:18]([C:21]([F:22])([F:23])[F:24])[CH2:19][CH2:20]3)[n:13]2)[cH:7][cH:8]1)([F:27])[F:28].[F:31][c:32]1[cH:33][c:34]([O:40][CH3:41])[c:35]([C:36]#[N:37])[cH:38][cH:39]1.[H-:29].[Na+:30]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[s:10][c:11]([CH2:25][O:26][c:32]3[cH:33][c:34]([O:40][CH3:41])[c:35]([C:36]#[N:37])[cH:38][cH:39]3)[c:12]([CH2:14][N:15]3[CH2:16][CH2:17][CH:18]([C:21]([F:22])([F:23])[F:24])[CH2:19][CH2:20]3)[n:13]2)[cH:7][cH:8]1)([F:27])[F:28]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-5ed4e321c6ee4a06b952fe01c6a33a27
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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