Tetrahydrofuran → 5-bromo-3-(1-methylpiperidin-4-yl)-1H-indole

HRID 1233289Notes

Reaction equation

HRID 1233289 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([C:11]3=[CH:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]3)[cH:6][nH:7][c:8]2[cH:9][cH:10]1.[H:18][H:19].[O:20]1[CH2:21][CH2:22][CH2:23][CH2:24]1.[Pt:25]=[O:26]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([CH:11]3[CH2:12][CH2:13][N:14]([CH3:17])[CH2:15][CH2:16]3)[cH:6][nH:7][c:8]2[cH:9][cH:10]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 82844Platinum oxide (PtO)HCID 149732085-bromo-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indoleHCID 178418361HCID 178418361, compound

Product 1

HCID 157453445-bromo-3-(1-methylpiperidin-4-yl)-1H-indole

Sources & evidence

ORD record
ord-999faf3d0643443baf7630cfcbca32d3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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