Acetone → 2-Methyl-2-[[4-thiophen-2-ylsulfonyl-1-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]piperazin-2-yl]methylamino]propanenitrile
Reaction equation
[CH3:30][C:31]([CH3:32])=[O:33].[CH3:34][Si:35]([CH3:36])([CH3:37])[C:38]#[N:39].[CH3:40][CH2:41][OH:42].[NH2:1][CH2:2][CH:3]1[N:4]([c:17]2[cH:18][cH:19][c:20]([C:23]([C:24]([F:25])([F:26])[F:27])([CH3:28])[OH:29])[cH:21][cH:22]2)[CH2:5][CH2:6][N:7]([S:9](=[O:10])(=[O:11])[c:12]2[s:13][cH:14][cH:15][cH:16]2)[CH2:8]1>>[NH:1]([CH2:2][CH:3]1[N:4]([c:17]2[cH:18][cH:19][c:20]([C:23]([C:24]([F:25])([F:26])[F:27])([CH3:28])[OH:29])[cH:21][cH:22]2)[CH2:5][CH2:6][N:7]([S:9](=[O:10])(=[O:11])[c:12]2[s:13][cH:14][cH:15][cH:16]2)[CH2:8]1)[C:31]([CH3:30])([CH3:32])[C:38]#[N:39]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-d8bae8499fde4fb3bb766368645b0681
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…