Tetrahydrofuran → 2-((5-(4-(bis(4-methoxybenzyl)amino)-6-methyl-1,3,5-triazin-2-yl)-6-(6-methoxypyridin-3-ylamino)pyridin-3-yl)(hydroxy)methyl)-4-bromo-N,N-dimethylbenzenesulfonamide
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]([CH3:12])[CH3:13])[cH:6][cH:7]1.[CH2:14]([Li:15])[CH2:16][CH2:17][CH3:18].[CH2:62]1[O:63][CH2:64][CH2:65][CH2:66]1.[CH3:19][O:20][c:21]1[cH:22][cH:23][c:24]([CH2:25][N:26]([c:27]2[n:28][c:29](-[c:34]3[c:35]([NH:42][c:43]4[cH:44][n:45][c:46]([O:49][CH3:50])[cH:47][cH:48]4)[n:36][cH:37][c:38]([CH:39]=[O:40])[cH:41]3)[n:30][c:31]([CH3:33])[n:32]2)[CH2:51][c:52]2[cH:53][cH:54][c:55]([O:58][CH3:59])[cH:56][cH:57]2)[cH:60][cH:61]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]([CH3:12])[CH3:13])[c:6]([CH:39]([c:38]2[cH:37][n:36][c:35]([NH:42][c:43]3[cH:44][n:45][c:46]([O:49][CH3:50])[cH:47][cH:48]3)[c:34](-[c:29]3[n:28][c:27]([N:26]([CH2:25][c:24]4[cH:23][cH:22][c:21]([O:20][CH3:19])[cH:61][cH:60]4)[CH2:51][c:52]4[cH:53][cH:54][c:55]([O:58][CH3:59])[cH:56][cH:57]4)[n:32][c:31]([CH3:33])[n:30]3)[cH:41]2)[OH:40])[cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-3eb2ea48ff904f05b629804004e86ea1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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