Dimethyl Sulfoxide → Tert-butyl 4-(2-oxo-1-(pyridin-3-yl)-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate

HRID 1233620Notes

Reaction equation

HRID 1233620 reaction equation
[C:40](=[O:41])([O-:42])[O-:43].[CH3:46][S:47]([CH3:48])=[O:49].[Cs+:44].[Cs+:45].[Cu:51][I:52].[I:1][c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1.[O:8]=[c:9]1[nH:10][cH:11][cH:12][c:13]([O:15][CH:16]2[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]2)[cH:14]1.[OH2:50].[OH:29][c:30]1[c:31]2[c:32]([cH:33][cH:34][cH:35][n:36]2)[cH:37][cH:38][cH:39]1>>[c:2]1(-[n:10]2[c:9](=[O:8])[cH:14][c:13]([O:15][CH:16]3[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]3)[cH:12][cH:11]2)[cH:3][n:4][cH:5][cH:6][cH:7]1

Participants

9

Reactant 8

HCID 679Dimethyl SulfoxideHCID 962WaterHCID 19238-HydroxyquinolineHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 707143-IodopyridineHCID 104967Cesium cation2×HCID 67366878Tert-butyl 4-(2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate

Product 1

HCID 67367446Tert-butyl 4-(2-oxo-1-(pyridin-3-yl)-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-fa29b7de45ca4fecbff9755c7009b0d7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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