Chloroform → Acetamide, N-(6,7-dihydro-9,10-dimethoxy-4-oxo-4H-pyrimido(6,1-a)isoquinolin-2-yl)-N-(2,4,6-trimethylphenyl)-

HRID 1233645Notes

Reaction equation

HRID 1233645 reaction equation
[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:37][C:38]([Cl:39])=[O:40].[CH3:8][O:9][c:10]1[cH:11][c:12]2[c:17]([cH:18][c:19]1[O:20][CH3:21])-[c:16]1[n:15]([c:25](=[O:26])[n:24][c:23]([NH:27][c:28]3[c:29]([CH3:36])[cH:30][c:31]([CH3:35])[cH:32][c:33]3[CH3:34])[cH:22]1)[CH2:14][CH2:13]2.[CH:41]([Cl:42])([Cl:43])[Cl:44]>>[CH3:8][O:9][c:10]1[cH:11][c:12]2[c:17]([cH:18][c:19]1[O:20][CH3:21])-[c:16]1[n:15]([c:25](=[O:26])[n:24][c:23]([N:27]([c:28]3[c:29]([CH3:36])[cH:30][c:31]([CH3:35])[cH:32][c:33]3[CH3:34])[C:38]([CH3:37])=[O:40])[cH:22]1)[CH2:14][CH2:13]2

Participants

5

Reactant 4

HCID 6212ChloroformHCID 6367Acetyl chlorideHCID 8471TriethylamineHCID 18694579,10-dimethoxy-2-(2,4,6-trimethylanilino)-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one

Product 1

HCID 3068155Acetamide, N-(6,7-dihydro-9,10-dimethoxy-4-oxo-4H-pyrimido(6,1-a)isoquinolin-2-yl)-N-(2,4,6-trimethylphenyl)-

Sources & evidence

ORD record
ord-1334bcde26874cd09dbf1f0e955e49ff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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