Tetrahydrofuran → 3-[(5-Ethyl-6-methoxy-2-methylpyridin3-yl)hydroxymethyl]benzonitrile
Reaction equation
[Br:6][c:7]1[c:8]([CH3:17])[n:9][c:10]([O:15][CH3:16])[c:11]([CH2:13][CH3:14])[cH:12]1.[C:18](#[N:19])[c:20]1[cH:21][c:22]([CH:23]=[O:24])[cH:25][cH:26][cH:27]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[c:7]1([CH:23]([c:22]2[cH:21][c:20]([C:18]#[N:19])[cH:27][cH:26][cH:25]2)[OH:24])[c:8]([CH3:17])[n:9][c:10]([O:15][CH3:16])[c:11]([CH2:13][CH3:14])[cH:12]1Participants
5
Sources & evidence
- ORD record
- ord-193983d6c87b4e31873529642799392b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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