Potassium Cation → 5'-(1-(benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-2'-(hydroxymethyl)-N,N-dimethylbiphenyl-4-carboxamide

HRID 1233969Notes

Reaction equation

HRID 1233969 reaction equation
[CH3:25][N:26]([C:27](=[O:28])[c:29]1[cH:30][cH:31][c:32]([B:35]([OH:36])[OH:37])[cH:33][cH:34]1)[CH3:38].[CH3:45][N:46]([CH3:47])[CH:48]=[O:49].[K+:39].[K+:40].[O-:41][C:42]([O-:43])=[O:44].[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([C:10]1([C:13](=[O:14])[NH:15][c:16]3[cH:17][c:18]([Br:24])[c:19]([CH2:22][OH:23])[cH:20][cH:21]3)[CH2:11][CH2:12]1)[cH:9]2>>[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([C:10]1([C:13](=[O:14])[NH:15][c:16]3[cH:17][c:18](-[c:32]4[cH:31][cH:30][c:29]([C:27]([N:26]([CH3:25])[CH3:38])=[O:28])[cH:34][cH:33]4)[c:19]([CH2:22][OH:23])[cH:20][cH:21]3)[CH2:11][CH2:12]1)[cH:9]2

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 35037674-(Dimethylcarbamoyl)phenylboronic AcidHCID 592062471-(benzo[d][1,3]dioxol-5-yl)-N-(3-bromo-4-(hydroxymethyl)phenyl)cyclopropanecarboxamide

Product 1

HCID 592065855'-(1-(benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-2'-(hydroxymethyl)-N,N-dimethylbiphenyl-4-carboxamide

Sources & evidence

ORD record
ord-8f9b97809ade43449f186c7eb6230221
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…