Dichloromethane → 1-Methyl-3-(1-{3-[3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][c:10]2[c:11]([n:14]([CH2:27][CH2:28][CH2:29][N:30]3[CH2:31][CH2:32][CH:33]([n:36]4[c:37](=[O:46])[n:38]([CH3:45])[c:39]5[c:40]4[cH:41][cH:42][cH:43][cH:44]5)[CH2:34][CH2:35]3)[n:15][c:16]2-[c:17]2[cH:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:47][CH2:48][Cl:49].[OH:50][C:51]([C:52]([F:53])([F:54])[F:55])=[O:56]>>[NH:8]1[CH2:9][c:10]2[c:11]([n:14]([CH2:27][CH2:28][CH2:29][N:30]3[CH2:31][CH2:32][CH:33]([n:36]4[c:37](=[O:46])[n:38]([CH3:45])[c:39]5[c:40]4[cH:41][cH:42][cH:43][cH:44]5)[CH2:34][CH2:35]3)[n:15][c:16]2-[c:17]2[cH:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]2)[CH2:12][CH2:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-97c6157552f94f3db864a21b993c18f9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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