Hydrochloric Acid → 4-Chloro-6-(4-(trifluoromethyl)phenyl)pyrimidine

HRID 1234055Notes

Reaction equation

HRID 1234055 reaction equation
[CH2:55]([O:56][CH2:57][CH3:58])[CH3:59].[CH3:1][C:2]1([CH3:3])[c:4]2[c:5]([cH:6][c:7]([NH:8][c:12]3[n:13][cH:14][n:15][c:16](-[c:18]4[cH:19][cH:20][c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]4)[cH:17]3)[cH:9][cH:10]2)[N:11]([C:28](=[O:29])[CH3:30])[CH2:31]1.[CH3:32][C:33]1([CH3:34])[c:35]2[c:36]([cH:37][c:38]([N+:39]([O-:40])=[O:41])[cH:42][cH:43]2)[NH:44][CH:45]1[C:46](=[O:47])[CH3:48].[ClH:54].[OH2:49].[OH2:50].[Sn:51]([Cl:52])[Cl:53]>>[c:12]1([Cl:52])[n:13][cH:14][n:15][c:16](-[c:18]2[cH:19][cH:20][c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]2)[cH:17]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 962Water2×HCID 3283Diethyl EtherHCID 24479Stannous ChlorideHCID 10455146HCID 10455146, compoundHCID 66876753HCID 66876753, compound

Product 1

HCID 167478374-Chloro-6-(4-(trifluoromethyl)phenyl)pyrimidine

Sources & evidence

ORD record
ord-7fbeb184d5e34c4995ed436061beeeee
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…