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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1234288Generated: October 31, 2026

Acetone → 3-(4-{[2-(4-Chloro-phenyl)-4-(2-hydroxy-ethyl)-thiazole-5-carbonyl]-amino}-2-methoxy-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/1234288

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetoneHCID 180—
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantBorohydrideHCID 28123—
ReactantLithium ionHCID 28486—
Reactant3-(4-{[2-(4-Chloro-phenyl)-4-methoxycarbonylmethyl-thiazole-5-carbonyl]-amino}-2-methoxy-phenoxy)-azetidine-1-carboxylic acid tert-butyl esterHCID 67463316—
Product3-(4-{[2-(4-Chloro-phenyl)-4-(2-hydroxy-ethyl)-thiazole-5-carbonyl]-amino}-2-methoxy-phenoxy)-azetidine-1-carboxylic acid tert-butyl esterHCID 59238509—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-e67079cfdbe64a489cd2d5106ca73f26
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)