Dichloromethane → {(3RS,4SR)-3-(3,4-Dichloro-phenyl)-4-[(RS)-1-(4-trifluoromethyl-phenoxy)-ethyl]pyrrolidin-1-yl}-[4-(2-dimethylamino-ethyl)-piperazin-1-yl]-methanone
Reaction equation
[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:37][N:38]([CH2:39][CH2:40][N:41]1[CH2:42][CH2:43][NH:44][CH2:45][CH2:46]1)[CH3:47].[Cl:1][c:2]1[cH:3][c:4]([CH:9]2[CH2:10][N:11]([C:27](=[O:28])[Cl:29])[CH2:12][CH:13]2[CH:14]([CH3:15])[O:16][c:17]2[cH:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]2)[cH:5][cH:6][c:7]1[Cl:8].[Cl:48][CH2:49][Cl:50]>>[Cl:1][c:2]1[cH:3][c:4]([CH:9]2[CH2:10][N:11]([C:27](=[O:28])[N:44]3[CH2:43][CH2:42][N:41]([CH2:40][CH2:39][N:38]([CH3:37])[CH3:47])[CH2:46][CH2:45]3)[CH2:12][CH:13]2[CH:14]([CH3:15])[O:16][c:17]2[cH:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]2)[cH:5][cH:6][c:7]1[Cl:8]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-d875921c297a45d6a92bd80ca50b8119
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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