Sulfuryl chloride → 2,3-dihydro-5H-benzo[f][1,4]oxazepine-4-sulfonyl chloride

HRID 1234478Notes

Reaction equation

HRID 1234478 reaction equation
[CH2:17]([N:18]([CH:19]([CH3:20])[CH3:21])[CH:22]([CH3:23])[CH3:24])[CH3:25].[CH3:26][O:27][c:28]1[cH:29][c:30]2[c:31]([cH:40][cH:41]1)[CH2:32][CH2:33][N:34]([S:35]([Cl:36])(=[O:37])=[O:38])[CH2:39]2.[O:1]1[CH2:2][CH2:3][NH:4][CH2:5][c:6]2[c:7]1[cH:8][cH:9][cH:10][cH:11]2.[S:12](=[O:13])(=[O:14])([Cl:15])[Cl:16]>>[O:1]1[CH2:2][CH2:3][N:4]([S:12](=[O:13])(=[O:14])[Cl:15])[CH2:5][c:6]2[c:7]1[cH:8][cH:9][cH:10][cH:11]2

Participants

5

Reactant 4

HCID 24648Sulfuryl chlorideHCID 81531DiisopropylethylamineHCID 218827752,3,4,5-Tetrahydro-1,4-benzoxazepineHCID 226656767-methoxy-3,4-dihydro-1H-isoquinoline-2-sulfonyl chloride

Product 1

HCID 226657772,3-dihydro-5H-benzo[f][1,4]oxazepine-4-sulfonyl chloride

Sources & evidence

ORD record
ord-5127ff82221a471892636d2159beb299
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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