Hydrochloric Acid → Carbonic acid 3-(5-bromo-3-fluoro-2-methyl-phenyl)-8-methoxy-2-oxo-1,8-diaza-spiro[4.5]dec-3-en-4-yl ester ethyl ester
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:23])[c:5]([CH3:22])[c:6]([C:8]2=[C:12]([OH:13])[C:11]3([NH:10][C:9]2=[O:21])[CH2:14][CH2:15][N:16]([O:19][CH3:20])[CH2:17][CH2:18]3)[cH:7]1.[CH3:37][C:38]#[N:39].[Cl:24][C:25](=[O:26])[O:27][CH2:28][CH3:29].[ClH:36].[cH:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1>>[Br:1][c:2]1[cH:3][c:4]([F:23])[c:5]([CH3:22])[c:6]([C:8]2=[C:12]([O:13][C:25](=[O:26])[O:27][CH2:28][CH3:29])[C:11]3([NH:10][C:9]2=[O:21])[CH2:14][CH2:15][N:16]([O:19][CH3:20])[CH2:17][CH2:18]3)[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d8f7f4bf053848ec8e54440d8d9ffa5a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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