Hydrochloric Acid → 6-Acetyl-2-(4-(4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)butyryl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine

HRID 1234862Notes

Reaction equation

HRID 1234862 reaction equation
[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][c:6]2[c:7]([cH:10][c:11]([C:13]([CH2:14][CH2:15][CH2:16][Cl:17])=[O:18])[s:12]2)[CH2:8][CH2:9]1.[ClH:19].[F:20][c:21]1[cH:22][c:23]2[c:24]([c:25]([CH:28]3[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]3)[n:26][o:27]2)[cH:34][cH:35]1>>[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][c:6]2[c:7]([cH:10][c:11]([C:13]([CH2:14][CH2:15][CH2:16][N:31]3[CH2:30][CH2:29][CH:28]([c:25]4[c:24]5[c:23]([cH:22][c:21]([F:20])[cH:35][cH:34]5)[o:27][n:26]4)[CH2:33][CH2:32]3)=[O:18])[s:12]2)[CH2:8][CH2:9]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8494213-(4-Piperidyl)-6-fluoro-1,2-benzisoxazoleHCID 214719026-Acetyl-2-(4-chlorobutyryl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine

Product 1

HCID 214719166-Acetyl-2-(4-(4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)butyryl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine

Sources & evidence

ORD record
ord-2364feec652c4e8ea217ae4e6deacb89
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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