Pyrazole → 2-[2-(4-Cyclobutylpiperazin-1-Yl)-2-Oxoethyl]-6-(1H-Pyrazol-1-Yl)-1,2,3,4-Tetrahydroisoquinoline
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][N:7]([CH2:12][C:13](=[O:14])[N:15]1[CH2:16][CH2:17][N:18]([CH:21]3[CH2:22][CH2:23][CH2:24]3)[CH2:19][CH2:20]1)[CH2:6][CH2:5]2.[C:40](=[O:41])([O-:42])[O-:43].[CH3:46][C:47]#[N:48].[CH:30](=[N:31][OH:32])[c:33]1[c:34]([OH:39])[cH:35][cH:36][cH:37][cH:38]1.[Cs+:44].[Cs+:45].[nH:25]1[n:26][cH:27][cH:28][cH:29]1>>[c:2]1(-[n:25]2[n:26][cH:27][cH:28][cH:29]2)[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][N:7]([CH2:12][C:13](=[O:14])[N:15]1[CH2:16][CH2:17][N:18]([CH:21]3[CH2:22][CH2:23][CH2:24]3)[CH2:19][CH2:20]1)[CH2:6][CH2:5]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-12917cf0d7cf47dcbe5ec483da14f071
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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